"Telltale plans to tie Season 2 in closer with the television adaptation of The Walking Dead, and is investigating the possibility of creating ties between characters in the television show and those in Season 2"
Ok, even if it is gonna have ties with the tv show, i still believe that it takes place in the comic's universe. Meaning, while Clem is surviving w/o Lee, Rick and his crew are off at the prison (i'd say around the time they just settle in, so they haven't met the Brian Blake yet.). Now they haven't introduced these following characters in the comics, but maybe they did that for a reason. maybe those two figures in the distance at the end of season 1 were not Christa and Omid. maybe it was Daryl and Merle. thoughts?