As many of you guys know Lee isn't in a position to be the protagonist of Season 2 so obviously he needs to be replaced, so here are my thoughts on possible replacements.
Clem would be the most obvious choice as she is the only character who is confirmed to be alive and it would allow you to see how her character develops but to honest I don't see her becoming the protagonist unless they jumped forward to a 16 year old or older clem, in Season 1 Lee's non canon deaths can be very graphic and while Clem can have non canon deaths I don't think they have a 9 year old having such gruesome deaths because too many people would complain or be put off playing, which would lessen the impact of the deaths.
Christa would be a good replacement for Lee I think, she is a rather strong character and like everyone she does have her weaknesses, but if the rumors are true and she is pregnant then that could cause problems with her being protagonist
Omid would be a fun guy to play as especially in dialogue but he doesn't seem to have lead character material, when we see them it is fairly clear that Christa is the one in charge out of the two of them, but having said that seeing him forced to take a lead role would be interesting.
Now that the video game Lilly is a separate character to the one in the comics they could bring her back into the game, and there is plenty they could do with her and they could explore how what she has been through has affected her (her father's death, murdering Carley/Doug) and if she came across Clementine again it would make for an interesting reunion.
They could bring her back, she is a largely unexplored character and it would be interesting to see her as a team player but considering how she gets around I think that playing as her would feel too much like Assassin's Creed.
In theory they could bring Kenny back but to be honest I think he should stay dead, There is more to Kenny's character we could explore but both of the ways he can die are fitting and I think it is a good place to leave him.
A new protagonist
They could bring in an entirely new protagonist, it would be interesting to see how a new lead would affect Clementine, Christa and Omid but especially Clementine as she as just lost both of her parents and Lee she may have trouble connecting to new people. They could of course have an entirely different setting but I think that would be a little repetitive and feel like season 1 all over again.
I'm wondering what you guys think so please vote on this poll or comment.