A flashback is shown with Lori, waiting outside the city where her parents are located. She is confronted by Shane, and she confides in him about how horrible she feels leaving Rick in the city. After a short conversation, Lori and Shane kiss, and Lori adds that she "needs him." The two of them end up having sex.
Back to the present, the survivors are burying Shane. The group then departs their camp using the RV. They continue on their journey until they need to clear some cars that are blocking the road. While clearing the cars the group meets Tyreese, his daughter Julie and her boyfriend Chris. Tyreese explains to Rick that a man in a store attempted to rape Julie. However, he was able to kill the man before he could rape her.
Rick doesn't judge Tyreese, and says anyone would have done that. Tyreese says he's beating himself up because he doesn't feel any guilt from it and the apocalypse has changed him. Suddenly, the two discover roamers. Tyreese marvels about the name 'roamer', and Rick explains they are zombies who just roam around, and killed Amy and Jim.
Tyreese and Rick take their primary weapons; hammer and hatchet. They trick the zombies, Rick takes one of them and Tyreese takes the other one. They beat them to death and say the situation is under control. They return to the RV and Rick tells Dale to drive around so they could look for some empty houses to stay in. Suddenly, they discover a crashed car in the road. Rick thinks they have to start moving it aside if they want to get to safety before dark.
Rick reveals he's glad they bumped into Tyreese and his family. They came in handy, especially because Tyreese is strong. Carol and Tyreese are having some eye contact.
At night, Tyreese says the people have a lot of food. Rick says he has to thank Glenn about it. He says he was just doing his part, but, Carol thinks they'd be much worse off without him. Tyreese agrees, he and Carol hold hands, and Glenn seems awful. Rick thinks it's honorable that Glenn risks his life for others and supplies.
While Rick is talking about finding Lori and Carl, Lori walks away. Rick catches her and asks what is wrong. Lori reveals that she is pregnant.
- Rick Grimes
- Lori Grimes
- Carl Grimes
- Shane (Flashback)
- First appearance of Tyreese.
- First appearance of Julie.
- First appearance of Chris.
- This is the first issue drawn by Charlie Adlard and Cliff Rathburn.
- Lori reveals that she's going to have a baby. Later in the series, the baby is named Judith.
- This issue takes place as the same time as Starved For Help from the Video Game.
- Originally, the survivors were meant to find the prison in this issue, as revealed in #108's Letter Hacks.
- When Tyreese and Rick are climbing down from the RV to kill two roamers a rifle is strapped to Rick's back, when he goes toward the roamers however it has disappeared.