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Nothing is known about Charlie's life before or as the outbreak began, other than that he was possibly homeless.
Charlie is seen along with two other residents from Woodbury. They are all presumed homeless. Charlie gets confused when Brian Blake asks if they have biters in the area. One of the other residents informs Charlie that Brian means the dead things.
The Prison Assault
During the second and final assault on the Prison, Billy Greene throws a grenade at a car, tearing shrapnel off the vehicle's front end, punching through Charlie's body, and apparently tearing a chunk out of his chest, causing him to hurl backwards and landing into the weeds.
Charlie is killed when Billy explodes a vehicle, sending jagged pieces of metal throughout the air and tears a chunk of Charlie's chest, killing him.